# Involuntary Weight Loss
Involuntary weight loss (IWL) is typically defined as a loss of weight >10 lbs or >5% of one’s body weight over a period of 6-12 months. The differential diagnosis for IWL is wide, and includes neoplastic and psychiatric causes, as well as diseases in nearly every organ system. Notably, exhaustive investigation will not yield a definitive diagnosis in up to a quarter of patients.
-- History, physical, MMSE, nutritional assessment, ADL/IADL assessment, medication review
-- Age appropriate cancer screening
-- CBC with diff, CMP, TFT, ESR, CRP, Ferritin, HIV testing
-- Nutrition referral